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Human PCSK7 activation kit by CRISPRa

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SKU
GA106107
PCSK7 CRISPRa kit - CRISPR gene activation of human proprotein convertase subtilisin/kexin type 7
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA500628 PCSK7 mouse monoclonal antibody, clone OTI1B8 (formerly 1B8) 100 ul
$447.00
RC203896 PCSK7 (Myc-DDK-tagged)-Human proprotein convertase subtilisin/kexin type 7 (PCSK7)
10 ug
$719.00

Other products for "PCSK7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCSK7
Locus ID 9159
Components

GA106107G1, PCSK7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA106107G2, PCSK7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA106107G3, PCSK7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004716
UniProt ID Q16549
Synonyms LPC; PC7; PC8; SPC7
Summary This gene encodes a member of the subtilisin-like proprotein convertase family, which includes proteases that process protein and peptide precursors trafficking through regulated or constitutive branches of the secretory pathway. It encodes a type 1 membrane bound protease that is expressed in many tissues, including neuroendocrine, liver, gut, and brain. The encoded protein undergoes an initial autocatalytic processing event in the ER and then sorts to the trans-Golgi network through endosomes where a second autocatalytic event takes place and the catalytic activity is acquired. This gene encodes one of the seven basic amino acid-specific members which cleave their substrates at single or paired basic residues. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes and plays a role in the regulation of iron metabolism. A t(11;14)(q23;q32) chromosome translocation associated with B-cell lymphoma occurs between this gene and its inverted counterpart. provided by RefSeq, Feb 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN403896 PCSK7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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