Human MBD4 activation kit by CRISPRa

SKU
GA105951
MBD4 CRISPRa kit - CRISPR gene activation of human methyl-CpG binding domain 4, DNA glycosylase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MBD4
Locus ID 8930
Components

GA105951G1, MBD4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105951G2, MBD4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105951G3, MBD4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001276270, NM_001276271, NM_001276272, NM_001276273, NM_003925
UniProt ID O95243
Synonyms MED1
Summary The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains an MBD domain at the N-terminus that functions both in binding to methylated DNA and in protein interactions and a C-terminal mismatch-specific glycosylase domain that is involved in DNA repair. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. provided by RefSeq, Jan 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN423909 MBD4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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