Human TIMELESS activation kit by CRISPRa

SKU
GA105942
TIMELESS CRISPRa kit - CRISPR gene activation of human timeless circadian regulator
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TIMELESS
Locus ID 8914
Components

GA105942G1, TIMELESS gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105942G2, TIMELESS gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105942G3, TIMELESS gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001330295, NM_003920, NR_138471
UniProt ID Q9UNS1
Synonyms hTIM; TIM; TIM1
Summary The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders. provided by RefSeq, Feb 2014
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Other Versions
SKU Description Size Price
KN408527 TIMELESS - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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