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Human GANP (MCM3AP) activation kit by CRISPRa

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SKU
GA105920
MCM3AP CRISPRa kit - CRISPR gene activation of human minichromosome maintenance complex component 3 associated protein
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350007 Rabbit Polyclonal Anti-MCM3AP Antibody
100 ul
$205.00
RC218026 MCM3AP (Myc-DDK-tagged)-Human minichromosome maintenance complex component 3 associated protein (MCM3AP)
10 ug
$1,666.00

Other products for "MCM3AP"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MCM3AP
Locus ID 8888
Components

GA105920G1, GANP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105920G2, GANP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105920G3, GANP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003906
UniProt ID O60318
Synonyms GANP; MAP80; SAC3
Summary The minichromosome maintenance protein 3 (MCM3) is one of the MCM proteins essential for the initiation of DNA replication. The protein encoded by this gene is a MCM3 binding protein. It was reported to have phosphorylation-dependent DNA-primase activity, which was up-regulated in antigen immunization induced germinal center. This protein was demonstrated to be an acetyltransferase that acetylates MCM3 and plays a role in DNA replication. The mutagenesis of a nuclear localization signal of MCM3 affects the binding of this protein with MCM3, suggesting that this protein may also facilitate MCM3 nuclear localization. This gene is expressed in the brain or in neuronal tissue. An allelic variant encoding amino acid Lys at 915, instead of conserved Glu, has been identified in patients with mild intellectual disability. provided by RefSeq, Jan 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN418026 MCM3AP - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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