Human HM74 (HCAR3) activation kit by CRISPRa

SKU
GA105885
HCAR3 CRISPRa kit - CRISPR gene activation of human hydroxycarboxylic acid receptor 3
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol HCAR3
Locus ID 8843
Components

GA105885G1, HM74 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105885G2, HM74 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105885G3, HM74 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_006018
UniProt ID P49019
Synonyms GPR109B; HCA3; HM74; Puma-g; PUMAG
Summary Receptor for 3-OH-octanoid acid mediates a negative feedback regulation of adipocyte lipolysis to counteract prolipolytic influences under conditions of physiological or pathological increases in beta-oxidation rates. Acts as a low affinity receptor for nicotinic acid. This pharmacological effect requires nicotinic acid doses that are much higher than those provided by a normal diet.UniProtKB/Swiss-Prot Function
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Documents
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Other Versions
SKU Description Size Price
KN408523 HCAR3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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