Human FLIP (CFLAR) activation kit by CRISPRa

SKU
GA105879
CFLAR CRISPRa kit - CRISPR gene activation of human CASP8 and FADD like apoptosis regulator
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CFLAR
Locus ID 8837
Components

GA105879G1, FLIP gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105879G2, FLIP gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105879G3, FLIP gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001127183, NM_001127184, NM_001202515, NM_001202516, NM_001202517, NM_001202518, NM_001202519, NM_001308042, NM_001308043, NM_003879, NM_001351590, NM_001351591, NM_001351592, NM_001351593, NM_001351594, NR_147241, NR_147242, NR_147243, NR_147244, NR_147245, NR_147246, NR_147247, NR_147248, NR_147249, NR_147250, NR_147251, NR_147252, NR_147253, NR_147255
UniProt ID O15519
Synonyms c-FLIP; c-FLIPL; c-FLIPR; c-FLIPS; CASH; CASP8AP1; Casper; CLARP; FLAME; FLAME-1; FLAME1; FLIP
Summary The protein encoded by this gene is a regulator of apoptosis and is structurally similar to caspase-8. However, the encoded protein lacks caspase activity and appears to be itself cleaved into two peptides by caspase-8. Several transcript variants encoding different isoforms have been found for this gene, and partial evidence for several more variants exists. provided by RefSeq, Feb 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN400608 CFLAR - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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