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Human SOCS2 activation kit by CRISPRa

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SKU
GA105877
SOCS2 CRISPRa kit - CRISPR gene activation of human suppressor of cytokine signaling 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC203163 SOCS2 (Myc-DDK-tagged)-Human suppressor of cytokine signaling 2 (SOCS2)
10 ug
$300.00

Other products for "SOCS2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SOCS2
Locus ID 8835
Components

GA105877G1, SOCS2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105877G2, SOCS2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105877G3, SOCS2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001270467, NM_001270468, NM_001270469, NM_001270470, NM_001270471, NM_003877
UniProt ID O14508
Synonyms CIS2; Cish2; SOCS-2; SSI-2; SSI2; STATI2
Summary This gene encodes a member of the suppressor of cytokine signaling (SOCS) family. SOCS family members are cytokine-inducible negative regulators of cytokine receptor signaling via the Janus kinase/signal transducer and activation of transcription pathway (the JAK/STAT pathway). SOCS family proteins interact with major molecules of signaling complexes to block further signal transduction, in part, by proteasomal depletion of receptors or signal-transducing proteins via ubiquitination. The expression of this gene can be induced by a subset of cytokines, including erythropoietin, GM-CSF, IL10, interferon (IFN)-gamma and by cytokine receptors such as growth horomone receptor. The protein encoded by this gene interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling. This gene has pseudogenes on chromosomes 20 and 22. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2012
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Documents
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Other Versions
SKU Description Size Price
KN403163 SOCS2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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