Human FGF17 activation kit by CRISPRa

SKU GA105866

FGF17 CRISPRa kit - CRISPR gene activation of human fibroblast growth factor 17

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: FGF17
• Locus ID: 8822
• Components:

  GA105866G1, FGF17 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105866G2, FGF17 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105866G3, FGF17 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001304478, NM_003867
• UniProt ID: O60258
• Synonyms: FGF-13; FGF-17; HH20
• Summary: This gene encodes a member of the fibroblast growth factor (FGF) family. Member of the FGF family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein is expressed during embryogenesis and in the adult cerebellum and cortex and may be essential for vascular growth and normal brain development. Mutations in this gene are the cause of hypogonadotropic hypogonadism 20 with or without anosmia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]