Human TRADD activation kit by CRISPRa

SKU
GA105784
TRADD CRISPRa kit - CRISPR gene activation of human TNFRSF1A associated via death domain
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRADD
Locus ID 8717
Components

GA105784G1, TRADD gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105784G2, TRADD gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105784G3, TRADD gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_003789, NM_153425, NM_001323552
UniProt ID Q15628
Synonyms Hs.89862
Summary The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN402599 TRADD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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