Human Apoptosis inhibitor 5 (API5) activation kit by CRISPRa

SKU
GA105653
API5 CRISPRa kit - CRISPR gene activation of human apoptosis inhibitor 5
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol API5
Locus ID 8539
Components

GA105653G1, Apoptosis inhibitor 5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105653G2, Apoptosis inhibitor 5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105653G3, Apoptosis inhibitor 5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001142930, NM_001142931, NM_001243747, NM_006595, NM_021112, NR_024625
UniProt ID Q9BZZ5
Synonyms AAC-11; AAC11
Summary This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. provided by RefSeq, Aug 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN404435 API5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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