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Human ITGA8 activation kit by CRISPRa

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SKU
GA105632
ITGA8 CRISPRa kit - CRISPR gene activation of human integrin subunit alpha 8
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC218936 ITGA8 (Myc-DDK-tagged)-Human integrin, alpha 8 (ITGA8)
10 ug
$925.00

Other products for "ITGA8"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGA8
Locus ID 8516
Components

GA105632G1, ITGA8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105632G2, ITGA8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105632G3, ITGA8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291494, NM_003638
UniProt ID P53708
Summary Integrins are heterodimeric transmembrane receptor proteins that mediate numerous cellular processes including cell adhesion, cytoskeletal rearrangement, and activation of cell signaling pathways. Integrins are composed of alpha and beta subunits. This gene encodes the alpha 8 subunit of the heterodimeric integrin alpha8beta1 protein. The encoded protein is a single-pass type 1 membrane protein that contains multiple FG-GAP repeats. This repeat is predicted to fold into a beta propeller structure. This gene regulates the recruitment of mesenchymal cells into epithelial structures, mediates cell-cell interactions, and regulates neurite outgrowth of sensory and motor neurons. The integrin alpha8beta1 protein thus plays an important role in wound-healing and organogenesis. Mutations in this gene have been associated with renal hypodysplasia/aplasia-1 (RHDA1) and with several animal models of chronic kidney disease. Alternate splicing results in multiple transcript variants encoding distinct isoforms. provided by RefSeq, Apr 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN418936 ITGA8 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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