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Human MAPKAP Kinase 3 (MAPKAPK3) activation kit by CRISPRa

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SKU
GA105342
MAPKAPK3 CRISPRa kit - CRISPR gene activation of human MAPK activated protein kinase 3
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC200358 MAPKAPK3 (Myc-DDK-tagged)-Human mitogen-activated protein kinase-activated protein kinase 3 (MAPKAPK3)
10 ug
$457.00

Other products for "MAPKAPK3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MAPKAPK3
Locus ID 7867
Components

GA105342G1, MAPKAP Kinase 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105342G2, MAPKAP Kinase 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105342G3, MAPKAP Kinase 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001243925, NM_001243926, NM_004635
UniProt ID Q16644
Synonyms 3PK; MAPKAP-K3; MAPKAP3; MAPKAPK-3; MK-3
Summary This gene encodes a member of the Ser/Thr protein kinase family. This kinase functions as a mitogen-activated protein kinase (MAP kinase)- activated protein kinase. MAP kinases are also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This kinase was shown to be activated by growth inducers and stress stimulation of cells. In vitro studies demonstrated that ERK, p38 MAP kinase and Jun N-terminal kinase were all able to phosphorylate and activate this kinase, which suggested the role of this kinase as an integrative element of signaling in both mitogen and stress responses. This kinase was reported to interact with, phosphorylate and repress the activity of E47, which is a basic helix-loop-helix transcription factor known to be involved in the regulation of tissue-specific gene expression and cell differentiation. Alternate splicing results in multiple transcript variants that encode the same protein. provided by RefSeq, Sep 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN400358 MAPKAPK3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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