Human ZNF148 activation kit by CRISPRa

SKU
GA105266
ZNF148 CRISPRa kit - CRISPR gene activation of human zinc finger protein 148
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ZNF148
Locus ID 7707
Components

GA105266G1, ZNF148 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105266G2, ZNF148 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105266G3, ZNF148 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_021964, NM_001348424, NM_001348425, NM_001348426, NM_001348427, NM_001348428, NM_001348429, NM_001348430, NM_001348431, NM_001348432, NM_001348433, NM_001348434, NM_001348436
UniProt ID Q9UQR1
Synonyms BERF-1; BFCOL1; HT-BETA; pHZ-52; ZBP-89; ZFP148
Summary The protein encoded by this gene is a member of the Kruppel family of zinc finger DNA binding proteins. The encoded protein activates transcription of the T-cell receptor and intestinal alkaline phosphatase genes but represses transcription of the ornithine decarboxylase, vimentin, gastrin, stomelysin, and enolase genes. Increased expression of this gene results in decreased patient survival rates from colorectal cancer, while mutations in this gene have been associated with global developmental delay, hypoplastic corpus callosum, and dysmorphic facies. provided by RefSeq, Feb 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN422687 ZNF148 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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