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Human splicing factor 1 (SF1) activation kit by CRISPRa

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SKU
GA105187
SF1 CRISPRa kit - CRISPR gene activation of human splicing factor 1
  $1,657.00
4 Weeks*

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Other products for "SF1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SF1
Locus ID 7536
Components

GA105187G1, splicing factor 1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105187G2, splicing factor 1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105187G3, splicing factor 1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001178030, NM_001178031, NM_004630, NM_201995, NM_201997, NM_201998, NR_033649, NR_033650, NM_001346363, NM_001346364, NM_001346409, NM_001346410
UniProt ID Q15637
Synonyms BBP; D11S636; MBBP; ZCCHC25; ZFM1; ZNF162
Summary This gene encodes a nuclear pre-mRNA splicing factor. The encoded protein specifically recognizes the intron branch point sequence at the 3' splice site, together with the large subunit of U2 auxiliary factor (U2AF), and is required for the early stages of spliceosome assembly. It also plays a role in nuclear pre-mRNA retention and transcriptional repression. The encoded protein contains an N-terminal U2AF ligand motif, a central hnRNP K homology motif and quaking 2 region which bind a key branch-site adenosine within the branch point sequence, a zinc knuckles domain, and a C-terminal proline-rich domain. Alternative splicing results in multiple transcript variants. provided by RefSeq, Oct 2016
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Resources
Other Versions
SKU Description Size Price
KN405846 SF1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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