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Human LXR beta (NR1H2) activation kit by CRISPRa

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SKU
GA105083
NR1H2 CRISPRa kit - CRISPR gene activation of human nuclear receptor subfamily 1 group H member 2
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC208381 NR1H2 (Myc-DDK-tagged)-Human nuclear receptor subfamily 1, group H, member 2 (NR1H2)
10 ug
$686.00

Other products for "NR1H2"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NR1H2
Locus ID 7376
Components

GA105083G1, LXR beta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105083G2, LXR beta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105083G3, LXR beta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001256647, NM_007121
UniProt ID P55055
Synonyms LXR-b; LXRB; NER; NER-I; RIP15; UNR
Summary The liver X receptors, LXRA (NR1H3; MIM 602423) and LXRB, form a subfamily of the nuclear receptor superfamily and are key regulators of macrophage function, controlling transcriptional programs involved in lipid homeostasis and inflammation. The inducible LXRA is highly expressed in liver, adrenal gland, intestine, adipose tissue, macrophages, lung, and kidney, whereas LXRB is ubiquitously expressed. Ligand-activated LXRs form obligate heterodimers with retinoid X receptors (RXRs; see MIM 180245) and regulate expression of target genes containing LXR response elements (summary by Korf et al., 2009 PubMed 19436111).supplied by OMIM, Jan 2010
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Documents
Resources
Other Versions
SKU Description Size Price
KN408381 NR1H2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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