Human PGP9.5 (UCHL1) activation kit by CRISPRa

SKU GA105058

UCHL1 CRISPRa kit - CRISPR gene activation of human ubiquitin C-terminal hydrolase L1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: UCHL1
• Locus ID: 7345
• Components:

  GA105058G1, PGP9.5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA105058G2, PGP9.5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA105058G3, PGP9.5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_004181
• UniProt ID: P09936
• Synonyms: HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1
• Summary: The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.[provided by RefSeq, Sep 2009]