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Human TTC3 activation kit by CRISPRa

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SKU
GA105003
TTC3 CRISPRa kit - CRISPR gene activation of human tetratricopeptide repeat domain 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA382920 TTC3 Rabbit polyclonal Antibody
100 ul
$410.00
RC221585 TTC3 (Myc-DDK-tagged)-Human tetratricopeptide repeat domain 3 (TTC3), transcript variant 2
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Other products for "TTC3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TTC3
Locus ID 7267
Components

GA105003G1, TTC3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA105003G2, TTC3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA105003G3, TTC3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001001894, NM_003316, NM_001320703, NM_001320704, NM_001330681, NM_001330682, NM_001330683, NM_001353936, NM_001353937, NM_001353938
UniProt ID P53804
Synonyms DCRR1; RNF105; TPRDIII
Summary E3 ubiquitin-protein ligase that mediates the ubiquitination and subsequent degradation of phosphorylated Akt (AKT1, AKT2 and AKT3) in the nucleus. Acts as a terminal regulator of Akt signaling after activation; its phosphorylation by Akt, which is a prerequisite for ubiquitin ligase activity, suggests the existence of a regulation mechanism required to control Akt levels after activation. Catalyzes the formation of 'Lys-48'-polyubiquitin chains. May play a role in neuronal differentiation inhibition via its interaction with CIT.UniProtKB/Swiss-Prot Function
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Documents
Resources
Other Versions
SKU Description Size Price
KN421541 TTC3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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