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Human TRAF3 activation kit by CRISPRa

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SKU
GA104969
TRAF3 CRISPRa kit - CRISPR gene activation of human TNF receptor associated factor 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA322870 Anti-TRAF3 rabbit polyclonal antibody
100 ul
$305.00
RC210417 TRAF3 (Myc-DDK-tagged)-Human TNF receptor-associated factor 3 (TRAF3), transcript variant 1
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Other products for "TRAF3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TRAF3
Locus ID 7187
Components

GA104969G1, TRAF3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104969G2, TRAF3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104969G3, TRAF3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001199427, NM_003300, NM_145725, NM_145726
UniProt ID Q13114
Synonyms CAP-1; CAP1; CD40bp; CRAF1; IIAE5; LAP1
Summary The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from, members of the TNF receptor (TNFR) superfamily. This protein participates in the signal transduction of CD40, a TNFR family member important for the activation of the immune response. This protein is found to be a critical component of the lymphotoxin-beta receptor (LTbetaR) signaling complex, which induces NF-kappaB activation and cell death initiated by LTbeta ligation. Epstein-Barr virus encoded latent infection membrane protein-1 (LMP1) can interact with this and several other members of the TRAF family, which may be essential for the oncogenic effects of LMP1. The protein also plays a role in the regulation of antiviral response. Mutations in this are associated with Encephalopathy, acute, infection-induced, herpes-specific 5. provided by RefSeq, Jul 2020
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Documents
Resources
Other Versions
SKU Description Size Price
KN410417 TRAF3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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