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Human 53BP1 (TP53BP1) activation kit by CRISPRa

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SKU
GA104943
TP53BP1 CRISPRa kit - CRISPR gene activation of human tumor protein p53 binding protein 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA807033 TP53BP1 mouse monoclonal antibody, clone OTI2H6 (formerly 2H6) 100 ul
$447.00
RC218016 TP53BP1 (Myc-DDK-tagged)-Human tumor protein p53 binding protein 1 (TP53BP1), transcript variant 3
10 ug
$2,485.00

Other products for "TP53BP1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TP53BP1
Locus ID 7158
Components

GA104943G1, 53BP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104943G2, 53BP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104943G3, 53BP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001141979, NM_001141980, NM_005657, NM_001355001
UniProt ID Q12888
Synonyms 53BP1; p202
Summary This gene encodes a protein that functions in the DNA double-strand break repair pathway choice, promoting non-homologous end joining (NHEJ) pathways, and limiting homologous recombination. This protein plays multiple roles in the DNA damage response, including promoting checkpoint signaling following DNA damage, acting as a scaffold for recruitment of DNA damage response proteins to damaged chromatin, and promoting NHEJ pathways by limiting end resection following a double-strand break. These roles are also important during V(D)J recombination, class switch recombination and at unprotected telomeres. Alternative splicing results in multiple transcript variants encoding different isoforms. provided by RefSeq, Aug 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN418016 TP53BP1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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