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Human TLR5 activation kit by CRISPRa

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SKU
GA104901
TLR5 CRISPRa kit - CRISPR gene activation of human toll like receptor 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA337067 Mouse Monoclonal TLR5 Antibody (19D759.2)
100 ug
$585.00
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10 ug
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Other products for "TLR5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TLR5
Locus ID 7100
Components

GA104901G1, TLR5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104901G2, TLR5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104901G3, TLR5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_003268
UniProt ID O60602
Synonyms MELIOS; SLE1; SLEB1; TIL3
Summary This gene encodes a member of the toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immune responses. These receptors recognize distinct pathogen-associated molecular patterns that are expressed on infectious agents. The protein encoded by this gene recognizes bacterial flagellin, the principal component of bacterial flagella and a virulence factor. The activation of this receptor mobilizes the nuclear factor NF-kappaB, which in turn activates a host of inflammatory-related target genes. Mutations in this gene have been associated with both resistance and susceptibility to systemic lupus erythematosus, and susceptibility to Legionnaire disease.provided by RefSeq, Dec 2009
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Documents
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Other Versions
SKU Description Size Price
KN415293 TLR5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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