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Human TFPI activation kit by CRISPRa

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SKU
GA104842
TFPI CRISPRa kit - CRISPR gene activation of human tissue factor pathway inhibitor
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA806051 TFPI mouse monoclonal antibody, clone OTI5A2 (formerly 5A2) 100 ul
$447.00
RC202098 TFPI (Myc-DDK-tagged)-Human tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) (TFPI), transcript variant 2
10 ug
$300.00

Other products for "TFPI"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TFPI
Locus ID 7035
Components

GA104842G1, TFPI gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104842G2, TFPI gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104842G3, TFPI gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001032281, NM_001318941, NM_006287, NM_001329239, NM_001329240, NM_001329241
UniProt ID P10646
Synonyms EPI; LACI; TFI; TFPI1
Summary This gene encodes a Kunitz-type serine protease inhibitor that regulates the tissue factor (TF)-dependent pathway of blood coagulation. The coagulation process initiates with the formation of a factor VIIa-TF complex, which proteolytically activates additional proteases (factors IX and X) and ultimately leads to the formation of a fibrin clot. The product of this gene inhibits the activated factor X and VIIa-TF proteases in an autoregulatory loop. Inhibition of the encoded protein restores hemostasis in animal models of hemophilia. This gene encodes multiple protein isoforms that differ in their inhibitory activity, specificity and cellular localization. provided by RefSeq, Jul 2016
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Resources
Other Versions
SKU Description Size Price
KN402098 TFPI - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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