Human TDO2 activation kit by CRISPRa

SKU
GA104812
TDO2 CRISPRa kit - CRISPR gene activation of human tryptophan 2,3-dioxygenase
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol TDO2
Locus ID 6999
Components

GA104812G1, TDO2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104812G2, TDO2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104812G3, TDO2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005651
UniProt ID P48775
Synonyms TDO; TO; TPH2; TRPO
Summary This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. provided by RefSeq, Feb 2012
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Documents
Resources
Other Versions
SKU Description Size Price
KN402777 TDO2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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