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Human ELOC activation kit by CRISPRa

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SKU
GA104775
ELOC CRISPRa kit - CRISPR gene activation of human elongin C
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC201950 TCEB1 (Myc-DDK-tagged)-Human transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) (TCEB1), transcript variant 1
10 ug
$150.00

Other products for "ELOC"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ELOC
Locus ID 6921
Components

GA104775G1, ELOC gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104775G2, ELOC gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104775G3, ELOC gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001204857, NM_001204858, NM_001204859, NM_001204860, NM_001204861, NM_001204862, NM_001204863, NM_001204864, NM_005648
UniProt ID Q15369
Synonyms eloC; SIII
Summary This gene encodes the protein elongin C, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been identified. provided by RefSeq, Mar 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN401950 TCEB1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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