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Human Spastin (SPAST) activation kit by CRISPRa

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SKU
GA104586
SPAST CRISPRa kit - CRISPR gene activation of human spastin
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA351199 Rabbit Polyclonal Anti-SPAST Antibody
100 ul
$205.00
RC214100 SPAST (Myc-DDK-tagged)-Human spastin (SPAST), transcript variant 2
10 ug
$544.00

Other products for "SPAST"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SPAST
Locus ID 6683
Components

GA104586G1, Spastin gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104586G2, Spastin gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104586G3, Spastin gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_014946, NM_199436, NM_001363823, NM_001363875
UniProt ID Q9UBP0
Synonyms ADPSP; FSP2; SPG4
Summary This gene encodes a member of the AAA (ATPases associated with a variety of cellular activities) protein family. Members of this protein family share an ATPase domain and have roles in diverse cellular processes including membrane trafficking, intracellular motility, organelle biogenesis, protein folding, and proteolysis. The use of alternative translational initiation sites in this gene results in a single transcript variant that can produce isoforms that differ in the length of their N-terminus and which thereby differ in the efficiency of their export from the nucleus to the cytoplasm. In addition, alternative splicing results in multiple transcript variants that encode isoforms that differ in other protein regions as well. One isoform of this gene has been shown to be a microtubule-severing enzyme that regulates microtubule abundance, mobility, and plus-end distribution. Mutations in this gene cause the most frequent form of autosomal dominant spastic paraplegia 4. provided by RefSeq, May 2018
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Documents
Resources
Other Versions
SKU Description Size Price
KN414100 SPAST - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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