Human EAAT2 (SLC1A2) activation kit by CRISPRa

SKU
GA104431
SLC1A2 CRISPRa kit - CRISPR gene activation of human solute carrier family 1 member 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SLC1A2
Locus ID 6506
Components

GA104431G1, EAAT2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104431G2, EAAT2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104431G3, EAAT2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001195728, NM_001252652, NM_004171
UniProt ID P43004
Synonyms EAAT2; GLT-1; HBGT
Summary This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Improper regulation of this gene is thought to be associated with several neurological disorders. Alternatively spliced transcript variants of this gene have been identified. provided by RefSeq, Jun 2017
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Documents
Resources
Other Versions
SKU Description Size Price
KN423924 SLC1A2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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