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Human RANTES (CCL5) activation kit by CRISPRa

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SKU
GA104316
CCL5 CRISPRa kit - CRISPR gene activation of human C-C motif chemokine ligand 5
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA806330 CCL5 mouse monoclonal antibody, clone OTI2A7 (formerly 2A7) 100 ul
$447.00
RC203799 CCL5 (Myc-DDK-tagged)-Human chemokine (C-C motif) ligand 5 (CCL5)
10 ug
$225.00

Other products for "CCL5"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol CCL5
Locus ID 6352
Components

GA104316G1, RANTES gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104316G2, RANTES gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104316G3, RANTES gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001278736, NM_002985
UniProt ID P13501
Synonyms D17S136E; eoCP; RANTES; SCYA5; SIS-delta; SISd; TCP228
Summary This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. provided by RefSeq, Jul 2013
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Documents
Resources
Other Versions
SKU Description Size Price
KN403799 CCL5 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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