OriGene Logo

Customer Login

Checkout as a new customer

Creating an account has many benefits:

  • See order and shipping status
  • Track order history
  • Check out faster
Create an Account

Human SCN1A activation kit by CRISPRa

Be the first to review this product
SKU
GA104290
SCN1A CRISPRa kit - CRISPR gene activation of human sodium voltage-gated channel alpha subunit 1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA326498 Mouse Monoclonal Anti-Nav1.1 Antibody
100 ug
$745.00
RC228708 SCN1A (Myc-DDK-tagged)-Human sodium channel, voltage-gated, type I, alpha subunit (SCN1A), transcript variant 1
10 ug
$2,487.00

Other products for "SCN1A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SCN1A
Locus ID 6323
Components

GA104290G1, SCN1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA104290G2, SCN1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA104290G3, SCN1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001165963, NM_001165964, NM_001202435, NM_006920, NM_001353948, NM_001353949, NM_001353950, NM_001353951, NM_001353952, NM_001353954, NM_001353955, NM_001353957, NM_001353958, NM_001353960, NM_001353961, NR_148667
UniProt ID P35498
Synonyms EIEE6; FEB3; FEB3A; FHM3; GEFSP2; HBSCI; NAC1; Nav1.1; SCN1; SMEI
Summary Voltage-dependent sodium channels are heteromeric complexes that regulate sodium exchange between intracellular and extracellular spaces and are essential for the generation and propagation of action potentials in muscle cells and neurons. Each sodium channel is composed of a large pore-forming, glycosylated alpha subunit and two smaller beta subunits. This gene encodes a sodium channel alpha subunit, which has four homologous domains, each of which contains six transmembrane regions. Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript. provided by RefSeq, Oct 2015
Reviews
Write Review
 
 
 
 
 

Be the first to review this product

Please note:
Only reviews with images are eligible for a $20/20€ Amazon gift card.
Reviews without images are eligible for a $10/10€ Amazon gift card.
For more details about the terms and conditions, please visit the promotion page.

Review image
Documents
Resources
Other Versions
SKU Description Size Price
KN420167 SCN1A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

file-alt Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

Related Products