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Human PTPRB activation kit by CRISPRa

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SKU
GA103931
PTPRB CRISPRa kit - CRISPR gene activation of human protein tyrosine phosphatase receptor type B
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC226479 PTPRB (Myc-DDK-tagged)-Human protein tyrosine phosphatase, receptor type, B (PTPRB), transcript variant 1
10 ug
$2,742.00

Other products for "PTPRB"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PTPRB
Locus ID 5787
Components

GA103931G1, PTPRB gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103931G2, PTPRB gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103931G3, PTPRB gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001109754, NM_001206971, NM_001206972, NM_001330204, NM_002837
UniProt ID P23467
Synonyms HPTP-BETA; HPTPB; PTPB; R-PTP-BETA; VEPTP
Summary The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular domain, a single transmembrane segment and one intracytoplasmic catalytic domain, thus belongs to receptor type PTP. The extracellular region of this PTP is composed of multiple fibronectin type_III repeats, which was shown to interact with neuronal receptor and cell adhesion molecules, such as contactin and tenascin C. This protein was also found to interact with sodium channels, and thus may regulate sodium channels by altering tyrosine phosphorylation status. The functions of the interaction partners of this protein implicate the roles of this PTP in cell adhesion, neurite growth, and neuronal differentiation. Alternate transcript variants encoding different isoforms have been found for this gene. provided by RefSeq, May 2011
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Documents
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Other Versions
SKU Description Size Price
KN414228 PTPRB - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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