Human PPP2R5B activation kit by CRISPRa

SKU GA103725

PPP2R5B CRISPRa kit - CRISPR gene activation of human protein phosphatase 2 regulatory subunit B'beta

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: PPP2R5B
• Locus ID: 5526
• Components:

  GA103725G1, PPP2R5B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103725G2, PPP2R5B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103725G3, PPP2R5B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_006244
• UniProt ID: Q15173
• Synonyms: B56B; PR61B
• Summary: The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B56 subfamily. [provided by RefSeq, Jul 2008]