Human PPAR delta (PPARD) activation kit by CRISPRa

SKU
GA103687
PPARD CRISPRa kit - CRISPR gene activation of human peroxisome proliferator activated receptor delta
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PPARD
Locus ID 5467
Components

GA103687G1, PPAR delta gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103687G2, PPAR delta gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103687G3, PPAR delta gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_001171818, NM_001171819, NM_001171820, NM_006238, NM_177435
UniProt ID Q03181
Synonyms FAAR; NR1C2; NUC1; NUCI; NUCII; PPARB
Summary This gene encodes a member of the peroxisome proliferator-activated receptor (PPAR) family. The encoded protein is thought to function as an integrator of transcriptional repression and nuclear receptor signaling. It may inhibit the ligand-induced transcriptional activity of peroxisome proliferator activated receptors alpha and gamma, though evidence for this effect is inconsistent. Expression of this gene in colorectal cancer cells may be variable but is typically relatively low. Knockout studies in mice suggested a role for this protein in myelination of the corpus callosum, lipid metabolism, differentiation, and epidermal cell proliferation. Alternative splicing results in multiple transcript variants encoding distinct protein isoforms. provided by RefSeq, Aug 2017
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Documents
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Other Versions
SKU Description Size Price
KN414735 PPARD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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