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Human PPAR alpha (PPARA) activation kit by CRISPRa

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SKU
GA103686
PPARA CRISPRa kit - CRISPR gene activation of human peroxisome proliferator activated receptor alpha
  $1,657.00
4 Weeks*

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Other products for "PPARA"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PPARA
Locus ID 5465
Components

GA103686G1, PPAR alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103686G2, PPAR alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103686G3, PPAR alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001001928, NM_001001929, NM_001001930, NM_005036, NM_032644, NM_001362872, NM_001362873
UniProt ID Q07869
Synonyms hPPAR; NR1C1; PPAR; PPARalpha
Summary Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN416176 PPARA - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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