Human PLCG 2 (PLCG2) activation kit by CRISPRa

SKU
GA103596
PLCG2 CRISPRa kit - CRISPR gene activation of human phospholipase C gamma 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PLCG2
Locus ID 5336
Components

GA103596G1, PLCG 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103596G2, PLCG 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103596G3, PLCG 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002661
UniProt ID P16885
Synonyms APLAID; FCAS3; PLC-gamma-2; PLC-IV
Summary The protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate to 1D-myo-inositol 1,4,5-trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in autoinflammation, antibody deficiency, and immune dysregulation syndrome and familial cold autoinflammatory syndrome 3. provided by RefSeq, Mar 2014
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Documents
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Other Versions
SKU Description Size Price
KN400442 PLCG2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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