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Human PIM1 activation kit by CRISPRa

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SKU
GA103557
PIM1 CRISPRa kit - CRISPR gene activation of human Pim-1 proto-oncogene, serine/threonine kinase
  $1,657.00
4 Weeks*

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Other products for "PIM1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PIM1
Locus ID 5292
Components

GA103557G1, PIM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103557G2, PIM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103557G3, PIM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001243186, NM_002648
UniProt ID P11309
Synonyms PIM
Summary The protein encoded by this gene belongs to the Ser/Thr protein kinase family, and PIM subfamily. This gene is expressed primarily in B-lymphoid and myeloid cell lines, and is overexpressed in hematopoietic malignancies and in prostate cancer. It plays a role in signal transduction in blood cells, contributing to both cell proliferation and survival, and thus provides a selective advantage in tumorigenesis. Both the human and orthologous mouse genes have been reported to encode two isoforms (with preferential cellular localization) resulting from the use of alternative in-frame translation initiation codons, the upstream non-AUG (CUG) and downstream AUG codons (PMIDs:16186805, 1825810).provided by RefSeq, Aug 2011
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Documents
Resources
Other Versions
SKU Description Size Price
KN405853 PIM1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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