Human PDE8A activation kit by CRISPRa

SKU
GA103448
PDE8A CRISPRa kit - CRISPR gene activation of human phosphodiesterase 8A
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE8A
Locus ID 5151
Components

GA103448G1, PDE8A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103448G2, PDE8A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103448G3, PDE8A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001243137, NM_002605, NM_173454, NM_173455, NM_173456, NM_173457
UniProt ID O60658
Synonyms HsT19550
Summary The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.provided by RefSeq, Jul 2011
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Other Versions
SKU Description Size Price
KN409169 PDE8A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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