Human PDE3B activation kit by CRISPRa

SKU
GA103437
PDE3B CRISPRa kit - CRISPR gene activation of human phosphodiesterase 3B
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE3B
Locus ID 5140
Components

GA103437G1, PDE3B gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103437G2, PDE3B gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103437G3, PDE3B gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Shipping Ambient
Reference Data
RefSeq NM_000922, NM_001363569, NM_001363570
UniProt ID Q13370
Synonyms cGIPDE1; HcGIP1
Summary Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological processes. May play a role in fat metabolism. Regulates cAMP binding of RAPGEF3. Through simultaneous binding to RAPGEF3 and PIK3R6 assembles a signaling complex in which the PI3K gamma complex is activated by RAPGEF3 and which is involved in angiogenesis.UniProtKB/Swiss-Prot Function
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Other Versions
SKU Description Size Price
KN419619 PDE3B - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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