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Human PDE1C activation kit by CRISPRa

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SKU
GA103434
PDE1C CRISPRa kit - CRISPR gene activation of human phosphodiesterase 1C
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

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50 ug
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Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PDE1C
Locus ID 5137
Components

GA103434G1, PDE1C gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103434G2, PDE1C gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103434G3, PDE1C gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001191056, NM_001191057, NM_001191058, NM_001191059, NM_001322055, NM_001322056, NM_001322057, NM_001322058, NM_001322059, NM_005020
UniProt ID Q14123
Synonyms cam-PDE 1C; hCam-3; Hcam3
Summary This gene encodes an enzyme that belongs to the 3'5'-cyclic nucleotide phosphodiesterase family. Members of this family catalyze hydrolysis of the cyclic nucleotides, cyclic adenosine monophosphate and cyclic guanosine monophosphate, to the corresponding nucleoside 5'-monophosphates. The enzyme encoded by this gene regulates proliferation and migration of vascular smooth muscle cells, and neointimal hyperplasia. This enzyme also plays a role in pathological vascular remodeling by regulating the stability of growth factor receptors, such as PDGF-receptor-beta. provided by RefSeq, Jul 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN405291 PDE1C - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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