Human PCK1 activation kit by CRISPRa

SKU
GA103414
PCK1 CRISPRa kit - CRISPR gene activation of human phosphoenolpyruvate carboxykinase 1
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol PCK1
Locus ID 5105
Components

GA103414G1, PCK1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103414G2, PCK1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103414G3, PCK1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002591
UniProt ID P35558
Synonyms PEPCK-C; PEPCK1; PEPCKC
Summary This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized. provided by RefSeq, Jul 2008
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Other Versions
SKU Description Size Price
KN404758 PCK1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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