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Human Neuropeptide Y (NPY) activation kit by CRISPRa

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SKU
GA103239
NPY CRISPRa kit - CRISPR gene activation of human neuropeptide Y
  $1,657.00
4 Weeks*

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Other products for "NPY"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NPY
Locus ID 4852
Components

GA103239G1, Neuropeptide Y gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103239G2, Neuropeptide Y gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103239G3, Neuropeptide Y gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000905
UniProt ID P01303
Synonyms PYY4
Summary This gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi. provided by RefSeq, Oct 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN406056 NPY - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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