Human NDUFS4 activation kit by CRISPRa

SKU GA103152

NDUFS4 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit S4

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: NDUFS4
• Locus ID: 4724
• Components:

  GA103152G1, NDUFS4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103152G2, NDUFS4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103152G3, NDUFS4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001318051, NM_002495, NR_134473, NR_134474, NR_134475
• UniProt ID: O43181
• Synonyms: AQDQ; CI-18
• Summary: This gene encodes an nuclear-encoded accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I, or NADH:ubiquinone oxidoreductase). Complex I removes electrons from NADH and passes them to the electron acceptor ubiquinone. Mutations in this gene can cause mitochondrial complex I deficiencies such as Leigh syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]