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Human NDUFA1 activation kit by CRISPRa

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SKU
GA103124
NDUFA1 CRISPRa kit - CRISPR gene activation of human NADH:ubiquinone oxidoreductase subunit A1
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA350206 Rabbit Polyclonal Anti-NDUFA1 Antibody
100 ul
$205.00
RC200616 NDUFA1 (Myc-DDK-tagged)-Human NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (NDUFA1), nuclear gene encoding mitochondrial protein
10 ug
$150.00

Other products for "NDUFA1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NDUFA1
Locus ID 4694
Components

GA103124G1, NDUFA1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103124G2, NDUFA1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103124G3, NDUFA1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_004541
UniProt ID O15239
Synonyms CI-MWFE; MWFE; ZNF183
Summary The human NDUFA1 gene codes for an essential component of complex I of the respiratory chain, which transfers electrons from NADH to ubiquinone. It has been noted that the N-terminal hydrophobic domain has the potential to be folded into an alpha-helix spanning the inner mitochondrial membrane with a C-terminal hydrophilic domain interacting with globular subunits of complex I. The highly conserved two-domain structure suggests that this feature is critical for the protein function and might act as an anchor for the NADH:ubiquinone oxidoreductase complex at the inner mitochondrial membrane. However, the NDUFA1 peptide is one of about 31 components of the "hydrophobic protein" (HP) fraction of complex I which is involved in proton translocation. Thus the NDUFA1 peptide may also participate in that function. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN400616 NDUFA1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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