Human MYO1A activation kit by CRISPRa

SKU GA103079

MYO1A CRISPRa kit - CRISPR gene activation of human myosin IA

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MYO1A
• Locus ID: 4640
• Components:

  GA103079G1, MYO1A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103079G2, MYO1A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103079G3, MYO1A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001256041, NM_005379
• UniProt ID: Q9UBC5
• Synonyms: BBMI; DFNA48; MIHC; MYHL
• Summary: This gene encodes a member of the myosin superfamily. The protein represents an unconventional myosin; it should not be confused with the conventional skeletal muscle myosin-1 (MYH1). Unconventional myosins contain the basic domains characteristic of conventional myosins and are further distinguished from class members by their tail domains. They function as actin-based molecular motors. Mutations in this gene have been associated with autosomal dominant deafness. Alternatively spliced variants have been found for this gene. [provided by RefSeq, Dec 2011]