Human MX1 activation kit by CRISPRa

SKU GA103045

MX1 CRISPRa kit - CRISPR gene activation of human MX dynamin like GTPase 1

Product Data

• Format: 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
• Target Symbol: MX1
• Locus ID: 4599
• Components:

  GA103045G1, MX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

  GA103045G2, MX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

  GA103045G3, MX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100077

• OTI Disclaimer: These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
• Shipping: Ambient

Reference Data

• RefSeq: NM_001144925, NM_001178046, NM_001282920, NM_002462
• UniProt ID: P20591
• Synonyms: IFI-78K; IFI78; MX; MxA
• Summary: This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]