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Human MVK activation kit by CRISPRa

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SKU
GA103044
MVK CRISPRa kit - CRISPR gene activation of human mevalonate kinase
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "MVK"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MVK
Locus ID 4598
Components

GA103044G1, MVK gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103044G2, MVK gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103044G3, MVK gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000431, NM_001114185, NM_001301182
UniProt ID Q03426
Synonyms LRBP; MK; MVLK; POROK3
Summary This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. provided by RefSeq, Jul 2014
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Documents
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Other Versions
SKU Description Size Price
KN401971 MVK - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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