Human IF 2(Mt) (MTIF2) activation kit by CRISPRa

SKU
GA103016
MTIF2 CRISPRa kit - CRISPR gene activation of human mitochondrial translational initiation factor 2
  $1,657.00
4 Weeks*
Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MTIF2
Locus ID 4528
Components

GA103016G1, IF 2(Mt) gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103016G2, IF 2(Mt) gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103016G3, IF 2(Mt) gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001005369, NM_001321001, NM_001321002, NM_001321003, NM_001321004, NM_001321005, NM_002453
UniProt ID P46199
Synonyms IF-2mt; mitochondrial translational initiation factor 2
Summary During the initiation of protein biosynthesis, initiation factor-2 (IF-2) promotes the binding of the initiator tRNA to the small subunit of the ribosome in a GTP-dependent manner. Prokaryotic IF-2 is a single polypeptide, while eukaryotic cytoplasmic IF-2 (eIF-2) is a trimeric protein. Bovine liver mitochondria contain IF-2(mt), an 85-kD monomeric protein that is equivalent to prokaryotic IF-2. The predicted 727-amino acid human protein contains a 29-amino acid presequence. Human IF-2(mt) shares 32 to 38% amino acid sequence identity with yeast IF-2(mt) and several prokaryotic IF-2s, with the greatest degree of conservation in the G domains of the proteins. provided by RefSeq, Mar 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN415473 MTIF2 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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