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Human MMP7 activation kit by CRISPRa

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SKU
GA102936
MMP7 CRISPRa kit - CRISPR gene activation of human matrix metallopeptidase 7
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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$447.00
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Other products for "MMP7"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol MMP7
Locus ID 4316
Components

GA102936G1, MMP7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102936G2, MMP7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102936G3, MMP7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_002423
UniProt ID P09237
Synonyms MMP-7; MPSL1; PUMP-1
Summary This gene encodes a member of the peptidase M10 family of matrix metalloproteinases (MMPs). Proteins in this family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded preproprotein is proteolytically processed to generate the mature protease. This secreted protease breaks down proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal hemopexin domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes on chromosome 11. This gene exhibits elevated expression levels in multiple human cancers. provided by RefSeq, Jan 2016
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Other Versions
SKU Description Size Price
KN401225 MMP7 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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