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Human ADAM11 activation kit by CRISPRa

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SKU
GA102852
ADAM11 CRISPRa kit - CRISPR gene activation of human ADAM metallopeptidase domain 11
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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100 ul
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RC220941 ADAM11 (Myc-DDK-tagged)-Human ADAM metallopeptidase domain 11 (ADAM11)
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Other products for "ADAM11"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ADAM11
Locus ID 4185
Components

GA102852G1, ADAM11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102852G2, ADAM11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102852G3, ADAM11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001318933, NM_002390, NM_021612
UniProt ID O75078
Synonyms MDC
Summary This gene encodes a member of the ADAM (a disintegrin and metalloprotease) protein family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The encoded preproprotein is proteolytically processed to generate the mature protease. This gene represents a candidate tumor suppressor gene for human breast cancer based on its location within a minimal region of chromosome 17q21 previously defined by tumor deletion mapping. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. provided by RefSeq, Jan 2016
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Documents
Resources
Other Versions
SKU Description Size Price
KN420941 ADAM11 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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