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Human SMAD3 activation kit by CRISPRa

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SKU
GA102776
SMAD3 CRISPRa kit - CRISPR gene activation of human SMAD family member 3
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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RC208749 SMAD3 (Myc-DDK-tagged)-Human SMAD family member 3 (SMAD3), transcript variant 1
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Other products for "SMAD3"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol SMAD3
Locus ID 4088
Components

GA102776G1, SMAD3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102776G2, SMAD3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102776G3, SMAD3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001145102, NM_001145103, NM_001145104, NM_005902
UniProt ID P84022
Synonyms HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MADH3
Summary The SMAD family of proteins are a group of intracellular signal transducer proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. The SMAD3 protein functions in the transforming growth factor-beta signaling pathway, and transmits signals from the cell surface to the nucleus, regulating gene activity and cell proliferation. It also functions as a tumor suppressor. Mutations in this gene are associated with aneurysms-osteoarthritis syndrome and Loeys-Dietz Syndrome 3. provided by RefSeq, Nov 2019
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Documents
Resources
Other Versions
SKU Description Size Price
KN408749 SMAD3 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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