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Human NBR1 activation kit by CRISPRa

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SKU
GA102769
NBR1 CRISPRa kit - CRISPR gene activation of human NBR1 autophagy cargo receptor
  $1,657.00
4 Weeks*

Frequently Bought Together (1)

RC215397 NBR1 (Myc-DDK-tagged)-Human neighbor of BRCA1 gene 1 (NBR1), transcript variant 1
10 ug
$884.00

Other products for "NBR1"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol NBR1
Locus ID 4077
Components

GA102769G1, NBR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102769G2, NBR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102769G3, NBR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_001291571, NM_001291572, NM_005899, NM_031858, NM_031862
UniProt ID Q14596
Synonyms 1A1-3B; IAI3B; M17S2; MIG19
Summary The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. provided by RefSeq, Apr 2014
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Documents
Resources
Other Versions
SKU Description Size Price
KN415342 NBR1 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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