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Human KRT6A activation kit by CRISPRa

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SKU
GA102615
KRT6A CRISPRa kit - CRISPR gene activation of human keratin 6A
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

TA322589 Anti-KRT6A Rabbit Polyclonal Antibody
100 ul
$305.00
RC204328 KRT6A (Myc-DDK-tagged)-Human keratin 6A (KRT6A)
10 ug
$525.00

Other products for "KRT6A"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol KRT6A
Locus ID 3853
Components

GA102615G1, KRT6A gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102615G2, KRT6A gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102615G3, KRT6A gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_005554
UniProt ID P02538
Synonyms CK-6C; CK-6E; CK6A; CK6C; CK6D; K6A; K6C; K6D; KRT6C; KRT6D; PC3
Summary The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. provided by RefSeq, Oct 2014
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Documents
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Other Versions
SKU Description Size Price
KN404328 KRT6A - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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