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Human Integrin beta 4 (ITGB4) activation kit by CRISPRa

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SKU
GA102480
ITGB4 CRISPRa kit - CRISPR gene activation of human integrin subunit beta 4
  $1,657.00
4 Weeks*

Frequently Bought Together (2)

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Other products for "ITGB4"

Specifications
Specifications
Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Target Symbol ITGB4
Locus ID 3691
Components

GA102480G1, Integrin beta 4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA102480G2, Integrin beta 4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA102480G3, Integrin beta 4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077
OTI Disclaimer These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
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Reference Data
RefSeq NM_000213, NM_001005619, NM_001005731, NM_001321123
UniProt ID P16144
Synonyms CD104; GP150
Summary Integrins are heterodimers comprised of alpha and beta subunits, that are noncovalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta 4 subunit, a receptor for the laminins. This subunit tends to associate with alpha 6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. provided by RefSeq, Jul 2008
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Documents
Resources
Other Versions
SKU Description Size Price
KN419381 ITGB4 - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. 1 kit
$1,657.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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